Post-Doctoral Fellow - Musculoskeletal Research
4.
0 Full-time 7 hours ago Full Job Description Faculty Description University of Colorado Anschutz Medical Campus Department:
Orthopedics Job Title:
Post-Doctoral Fellow Position #:
00807249 - Requisition #:
29073 Job
Summary:
The Ackert-Bicknell laboratory in the Colorado Program for Musculoskeletal Research, within the Department of Orthopedics is seeking to fill the position of Postdoctoral Fellow.
The Fellow will conduct research centered on the identification of fundamental mechanisms by which dietary fat impacts the physiology of the mesenchymal cells of bone and how this in turn affects development of the whole vertebrate skeleton.
An emphasis of this work will be the identification of gene by environment interactions that impact bone physiology.
This project involves the application of cutting-edge approaches in vivo and in vitro, including zebrafish, mouse and cell models combined with big data '-omics' approaches.
The results from this study are anticipated to substantially increase our understanding of when and how modifiable dietary factors impact skeletal development and will fill in gaps in knowledge left by other approaches such as Genome Wide Association Studies.
This research will be conducted in collaboration with Dr.
David Karasik at the Faculty of Medicine of Bar-Ilan University, Safed, Israel.
The postdoctoral fellow will be in constant communication with the Israeli counterpart to coordinate experiments being conducted as part of the larger research project.
This position is planned to last 2 years, with an option for an extended year.
Key
Responsibilities:
Zebrafish husbandry, genotyping, skeletal and non-skeletal tissue harvest.
Collection of skeletal imaging information from larval, juvenile and adult zebrafish and harvested tissue samples.
Generation of stable and chimeric transgenic zebrafish (so called CRISPANTS).
Collection of skeletal imaging information using live mice and harvested mouse tissue samples.
Molecular analyses of fish, mouse and human tissues, including Western blotting, qPCR/PCR, immunohistochemistry and immunofluorescence Culture of primary cells and established cell lines.
Transfection of cells with viral vectors or plasmid vectors.
Histology of musculoskeletal tissues (rodent and fish), including embedding, sectioning and imaging.
Collection of and analysis of RNAseq transcriptomic data.
Bioinformatic analysis using large data sets such as genomic, proteomic, lipidomic and transcriptomic data.
Manuscript preparation, presentation at scientific meetings Why Join Us:
The University of Colorado (CU) is one of the nation's premier educational and research institutions.
The Colorado Program for Musculoskeletal Rsearch (CPMR), of which Dr.
Ackert-Bicknell (PI) is a member, in the Department of Orthopedics at CU has undergone a rapid expansion with the last four years to become one of the top funded Orthopedic Departments in the US.
The CPMR is comprised of a core group of orthopedic faculty pursuing a cutting-edge basic, translational and clinical studies of the musculoskeletal system.
Our research encompasses a broad array of topics including genetics of osteoporosis & scoliosis, bone biology, arthritis & joint biology, skeletal healing from the spine to limbs, stem cell biology & tissue engineering, growth plate injury & repair, brain injury-skeleton connections, and orthopedic pain management.
The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off - vacation, sick, and holidays and more.
To see what benefits are available, please visit:
Diversity and Equity:
The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff.
The university strives to promote a culture of inclusiveness, respect, communication and understanding.
We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ
community and all veterans.
The University of Colorado is committed to diversity and equality in education and employment.
Qualifications:
Minimum
Qualifications:
Applicants must meet minimum qualifications at the time of hire.
A PhD in Biology, Genetics, Biochemistry or related field.
Equivalent degrees may be considered.
At least three years of experience in Biological Research.
A strong publication record is required, including first authorship publications stemming from their previous research.
Preferred
Qualifications:
3
years of experience working with laboratory zebrafish and mice The CPMR has a funded T32 training grant and successful candidate will have the opportunity to compete for on the prestigious seats in this training program.
Therefore, preference will be given to those candidates eligible to receive NIH funded training support.
The successful candidate may have the opportunity to travel Dr.
Karasik's laboratory in Safed, Israel.
Eligibility to obtain a visa to travel to Israel is preferred, but not required.
Knowledge, Skills and Abilities:
Understanding of skeletal physiology and genetics Ability to work both in a team environment and independently Strong organizational and record-keeping skills Strong communication skills, both verbal and written Computer skills in both Mac and PC environments and use of standard programs such as Word and Excel Bioinformatics and or programming expertise in languages such as R and Python A strong understanding of Biostatistics.
This is a training position and is not eligible to obtain Employer sponsored US permanent residency status.
How to Apply:
For full consideration, please submit the following document(s):
A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position Curriculum vitae / Resume Five professional references including name, address, phone number (mobile number if appropriate), and email address Applications are accepted electronically ONLY at www.
cu.
edu/cu-careers.
Questions should be directed to:
Lindsey Renn, lindsey.
renn@cuanschutz.
edu Screening of Applications Begins:
Immediately and continues until position is filled.
For best consideration, apply by (April 30, 2023).
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE:
The budgeted salary for this position is $56,484 (NIH Post Doc Year 0 salary) The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
This position is not eligible for overtime compensation unless it is non-exempt.
Your total compensation goes beyond the number on your paycheck.
The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator:
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process.
To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.
adacoordinator@ucdenver.
edu.
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors.
To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date.
Information regarding this requirement, and exemptions can be found at:
Unit-Specific Exemptions:
Anschutz Campus - Accommodations may be granted for medical or religious reasons.
The University of Colorado seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.
We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.
Application Materials Required:
Cover Letter, Resume/CV, List of References Job Category:
Faculty Primary Location:
Aurora Department:
U0001 - DENVER & ANSCHUTZ MED CAMPUS - 20259 - SOM-ORTHO GENERAL OPERATIONS Schedule:
Full-time Posting Date:
Feb 22, 2023 Unposting Date:
Ongoing Posting Contact Name:
Lindsey Renn Posting Contact Email:
lindsey.
renn@cuanschutz.
edu Position Number:
00807249.
Estimated Salary: $20 to $28 per hour based on qualifications.
0 Full-time 7 hours ago Full Job Description Faculty Description University of Colorado Anschutz Medical Campus Department:
Orthopedics Job Title:
Post-Doctoral Fellow Position #:
00807249 - Requisition #:
29073 Job
Summary:
The Ackert-Bicknell laboratory in the Colorado Program for Musculoskeletal Research, within the Department of Orthopedics is seeking to fill the position of Postdoctoral Fellow.
The Fellow will conduct research centered on the identification of fundamental mechanisms by which dietary fat impacts the physiology of the mesenchymal cells of bone and how this in turn affects development of the whole vertebrate skeleton.
An emphasis of this work will be the identification of gene by environment interactions that impact bone physiology.
This project involves the application of cutting-edge approaches in vivo and in vitro, including zebrafish, mouse and cell models combined with big data '-omics' approaches.
The results from this study are anticipated to substantially increase our understanding of when and how modifiable dietary factors impact skeletal development and will fill in gaps in knowledge left by other approaches such as Genome Wide Association Studies.
This research will be conducted in collaboration with Dr.
David Karasik at the Faculty of Medicine of Bar-Ilan University, Safed, Israel.
The postdoctoral fellow will be in constant communication with the Israeli counterpart to coordinate experiments being conducted as part of the larger research project.
This position is planned to last 2 years, with an option for an extended year.
Key
Responsibilities:
Zebrafish husbandry, genotyping, skeletal and non-skeletal tissue harvest.
Collection of skeletal imaging information from larval, juvenile and adult zebrafish and harvested tissue samples.
Generation of stable and chimeric transgenic zebrafish (so called CRISPANTS).
Collection of skeletal imaging information using live mice and harvested mouse tissue samples.
Molecular analyses of fish, mouse and human tissues, including Western blotting, qPCR/PCR, immunohistochemistry and immunofluorescence Culture of primary cells and established cell lines.
Transfection of cells with viral vectors or plasmid vectors.
Histology of musculoskeletal tissues (rodent and fish), including embedding, sectioning and imaging.
Collection of and analysis of RNAseq transcriptomic data.
Bioinformatic analysis using large data sets such as genomic, proteomic, lipidomic and transcriptomic data.
Manuscript preparation, presentation at scientific meetings Why Join Us:
The University of Colorado (CU) is one of the nation's premier educational and research institutions.
The Colorado Program for Musculoskeletal Rsearch (CPMR), of which Dr.
Ackert-Bicknell (PI) is a member, in the Department of Orthopedics at CU has undergone a rapid expansion with the last four years to become one of the top funded Orthopedic Departments in the US.
The CPMR is comprised of a core group of orthopedic faculty pursuing a cutting-edge basic, translational and clinical studies of the musculoskeletal system.
Our research encompasses a broad array of topics including genetics of osteoporosis & scoliosis, bone biology, arthritis & joint biology, skeletal healing from the spine to limbs, stem cell biology & tissue engineering, growth plate injury & repair, brain injury-skeleton connections, and orthopedic pain management.
The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off - vacation, sick, and holidays and more.
To see what benefits are available, please visit:
Diversity and Equity:
The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff.
The university strives to promote a culture of inclusiveness, respect, communication and understanding.
We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ
community and all veterans.
The University of Colorado is committed to diversity and equality in education and employment.
Qualifications:
Minimum
Qualifications:
Applicants must meet minimum qualifications at the time of hire.
A PhD in Biology, Genetics, Biochemistry or related field.
Equivalent degrees may be considered.
At least three years of experience in Biological Research.
A strong publication record is required, including first authorship publications stemming from their previous research.
Preferred
Qualifications:
3
years of experience working with laboratory zebrafish and mice The CPMR has a funded T32 training grant and successful candidate will have the opportunity to compete for on the prestigious seats in this training program.
Therefore, preference will be given to those candidates eligible to receive NIH funded training support.
The successful candidate may have the opportunity to travel Dr.
Karasik's laboratory in Safed, Israel.
Eligibility to obtain a visa to travel to Israel is preferred, but not required.
Knowledge, Skills and Abilities:
Understanding of skeletal physiology and genetics Ability to work both in a team environment and independently Strong organizational and record-keeping skills Strong communication skills, both verbal and written Computer skills in both Mac and PC environments and use of standard programs such as Word and Excel Bioinformatics and or programming expertise in languages such as R and Python A strong understanding of Biostatistics.
This is a training position and is not eligible to obtain Employer sponsored US permanent residency status.
How to Apply:
For full consideration, please submit the following document(s):
A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position Curriculum vitae / Resume Five professional references including name, address, phone number (mobile number if appropriate), and email address Applications are accepted electronically ONLY at www.
cu.
edu/cu-careers.
Questions should be directed to:
Lindsey Renn, lindsey.
renn@cuanschutz.
edu Screening of Applications Begins:
Immediately and continues until position is filled.
For best consideration, apply by (April 30, 2023).
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE:
The budgeted salary for this position is $56,484 (NIH Post Doc Year 0 salary) The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
This position is not eligible for overtime compensation unless it is non-exempt.
Your total compensation goes beyond the number on your paycheck.
The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator:
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process.
To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.
adacoordinator@ucdenver.
edu.
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors.
To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date.
Information regarding this requirement, and exemptions can be found at:
Unit-Specific Exemptions:
Anschutz Campus - Accommodations may be granted for medical or religious reasons.
The University of Colorado seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.
We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.
Application Materials Required:
Cover Letter, Resume/CV, List of References Job Category:
Faculty Primary Location:
Aurora Department:
U0001 - DENVER & ANSCHUTZ MED CAMPUS - 20259 - SOM-ORTHO GENERAL OPERATIONS Schedule:
Full-time Posting Date:
Feb 22, 2023 Unposting Date:
Ongoing Posting Contact Name:
Lindsey Renn Posting Contact Email:
lindsey.
renn@cuanschutz.
edu Position Number:
00807249.
Estimated Salary: $20 to $28 per hour based on qualifications.
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